Won t stop bleeding disease
A bleeding disorder occurs when blood does not clot fast enough. This results in too much bleeding or bleeding that lasts a long time.
Normal blood clotting is called coagulation. This complex process involves platelets and clotting or coagulation factors.
Platelets are special blood cells.
Clotting or coagulation factors are types of protein in blood.
Platelets and coagulation factors clump together to heal broken blood vessels. This helps control bleeding. A delicate balance of coagulation factors promote healthy bleeding and clotting.
Blood clotting disorders occur when:
Clotting factors are missing or damaged.
The blood has too few platelets.
Platelets don't work correctly.
Symptoms of bleeding problems
People with bleeding disorders may experience the following symptoms:
Cuts that bleed excessively
Unexpected or sudden bruising
Small purple or red spots under the skin. These are called petechiae.
Blood in vomit. It often resembles coffee grounds.
Black or bloody bowel movements
Red or pink urine
Dizziness, headaches, or changes in vision
Heavier- or longer-than-usual menstrual periods in women
Talk with your health care team about any symptoms you experience. In particular, mention new symptoms or a change in symptoms.
Causes of bleeding problems
Sometimes a person inherits a bleeding disorder. This means it is genetic and runs in the family. Other bleeding problems result from illness or treatment with specific drugs.
Causes of bleeding problems include the following:
Inherited disorders. Hemophilia and von Willebrand’s disease are 2 types. With
hemophilia, blood doesn't clot normally. With von Willebrand's disease, clotting factors are missing or do not work well.
Vitamin K deficiency
Cancer that begins in or spreads to the liver
Other liver disorders. These include hepatitis and cirrhosis. Hepatitis is an infection of the liver. Cirrhosis is scarring of the liver.
Long-term use of powerful antibiotics or anticoagulants. Anticoagulants are medications that thin the blood.
Drugs called angiogenesis inhibitors. These prevent the growth and development of new blood vessels.
Thrombocytopenia. which is an unusually low level of platelets
Anemia. which is an unusually low level of red blood cells
Other disorders unrelated to cancer
Diagnosing bleeding problems
Your doctor will review your medical history and perform a physical examination. And, a nurse or laboratory technician will draw blood. The blood will be used for several blood tests:
Tests to check the speed of blood clotting
Tests to check for blood protein deficiencies
Treating bleeding problems
Treatment to relieve symptoms and side effects is an important part of cancer care. This approach is called supportive or palliative care. It helps meet the patient’s physical, emotional, and social needs.
When possible, doctors treat a bleeding disorder’s underlying cause, such as cancer or liver disease.
These are additional treatments:
Vitamin K injection
Drugs that help blood to clot
Blood plasma or platelet transfusions
Other medications to treat platelet problems. These include hydroxyurea (Droxia, Hydrea) and oprelvekin (Neumega).